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Canine Appendicular Osteosarcoma

Colorado State University, Colorado:
Impact of Palladia/Piroxicam/Cyclophosphamide maintenance therapy on the survival time. Carboplatin will be provided at no cost to the owner. Once carboplatin therapy is completed, Palladia will be provided by the study and certain pre-determined financial incentives will be given at each recheck visit (up to a total of $650 throughout the course of the study). Details

UC Davis School of Veterinary Medicine, California:
Impact of Palladia/Piroxicam/Cyclophosphamide maintenance therapy on the survival time. Carboplatin will be provided at no cost to the owner. Once carboplatin therapy is completed, Palladia will be provided by the study and certain pre-determined financial incentives will be given at each recheck visit (up to a total of $650 throughout the course of the study). Details

Measure the reduction in bone strength. This study provides the computed tomography of the forelimbs and $325 toward total cost of your dog’s anesthesia, which covers the first two hours of anesthesia. Details

University of Illinois Cancer Care Clinic and Comparative Oncology Research Laboratory, Illinois:
Development of bone-seeking nanoparticles encapsulating doxorubicin. The study will pay for the initial examination and recheck fees, blood work (initial and weekly rechecks), imaging studies and hospitalization (initial and weekly rechecks), leg radiographs, oral analgesics for 21 days, and credit pet owners with $1500.00 for limb amputation. Details

Treatment with Metronomic Chemotherapy and Palladia. The study will provide free carboplatin therapy for all study patients, as well as partially pay all scheduled follow up evaluations. Details

Tufts University – Cummings School of Veterinary Medicine, Massachusetts:
Efficacy of Metronomic Chemotherapy. This study is not funded. Details
Evaluation of Pamidronate. This study is not funded. Details

University of Minnesota, Minnesota:
Evaluation of Palladia/Piroxicam/Cyclophosphamide Therapy. The study will cover the costs of the carboplatin and Palladia, plus a credit at each recheck ($50-$75/visit) for a total of $650 over eight months. Details

University of Missouri-Columbia Veterinary Medical Teaching Hospital, Missouri:
Evaluation of Palladia/Piroxicam/Cyclophosphamide Therapy. The study will cover the costs of the carboplatin and Palladia. Financial incentive of $25-75.00/visit for follow-up exams, not to exceed $650.00. Details

Veterinary Cancer Care, New Mexico:
Effectiveness of Zoledronate. This study is partially funded. Details

NC State College of Veterinary Medicine, North Carolina:
Evaluation of Palladia. The study will cover the costs of Palladia and blood work associated with drug monitoring. Details

Ohio State University College of Veterinary Medicine, Ohio:
Evaluate the activity of piroxicam/cyclophosphamide versus Palladia/piroxicam/cyclophosphamide. The study will provide Palladia free of cost for duration of study and beyond. The study will provide a total of $1,130.00 divided between the visits to help alleviate the costs. That includes paying for the total cost of carboplatin and some of the recheck visits and tests. Details

LSU School of Veterinary Medicine, Louisianna:
Evaluation of treatment with amputation, IL-12 and standard chemotherapy. Details

University of Pennsylvania - Veterinary Clinical Investigations Center, Pennsylvania:
Determine whether a recombinant L. moncytogenes vaccine can make the dog’s own immune system attack the tumor. Complete staging of disease at the time of enrollment (blood work, urinalysis, immune function assessment, chest x-rays, cardiac evaluation). Three Listeria monocytogenes vaccines. Hospitalization for observation. Blood work, urinalysis and cardiac evaluation every three weeks for a total of 9 weeks
Routine staging every 2 months following last vaccine administration (blood work, urinalysis, immune assessment, chest x-rays, cardiac evaluation). Four doses of carboplatin chemotherapy for dog's whose tumor expresses Her-2/neu (diagnosed after limb amputation). Details

University of Wisconsin-Madison, Wisconsin:
Compare the combination of piroxicam and cyclophosphamide, with or without Palladia, in dogs with OSA following amputation and standard of care treatment consisting of 4 cycles of carboplatin. The study will pay for the carboplatin (total savings of approximately $600-800). The owner will receive a credit at each recheck visit (approximately $50-75/visit) following initiation of oral therapy totaling $650 over 8 months. Details

Canine Osteosarcoma

University of Minnesota, Minnesota:
This is a nationwide clinical trial looking at the safety and potential effectiveness of a new therapeutic treatment. The study pays for exams, treatment, some diagnostic tests, and management of any treatment side effects. Details

Animal Clinical Investigation, LLC, National Research:
Study of osteosarcoma in Great Pyrenees. This study is not funded. Details

Evaluate treated with modified anaerobic bacteria. Study drug, diagnostic tests, and follow-up exams will be paid for by the study sponsor. In the event that side effects are attributed to the study drug, the study will pay for medical management of the side effects. Details

Ohio State University College of Veterinary Medicine, Ohio:
Describe the safety and efficacy of three dosages of an intravenous infusion of C. novyi-NT spores. The study sponsor will pay for therapeutic agent, diagnostic tests, and follow-up evaluations. In the event that side effects are noted and attributed to the therapeutic agent, the study will pay for medical management of the side effects. Details

Evaluate the safety and tolerance of KPT-335. The sponsor will cover study associated costs for screening, exam fees, lab work and up to $750 for any adverse events or concomitant medication. Details

University of Wisconsin-Madison, Wisconsin:
Nationwide study to evaluate a novel cancer treatment the modified anaerobic bacterium. This study will pay for the therapeutic agent, diagnostic tests required by the study, and follow-up evaluations. In the event that side effects are noted and attributed to the therapeutic agent, the study will pay for medical management of the side effects. Details

Specimen collection to aid in research. Pfizer Inc. CCOGC Biospecimen Repository. The cost of surgical biopsy collection, a necessary diagnostic step in the majority of patient work-ups, is completely covered in most cases (unless involving open cavity collection).


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