Looking For The Best Pain Reliever For Dogs?

Here’s a look at our favorites, including our top pick – Vet’s Best Aches + Pains Dog Supplements.

#1 Best Pain Reliever For Dogs


Aches and pains aren’t just a problem that only humans deal with. Mobility, vitality, and joint support are an important part of your dog’s happiness, and any decreases in these areas can negatively impact their quality of life. Over time, dogs can develop joint pain and sore muscles from constant running, jumping, and exercising.

Years of wear and tear can break down cartilage and result in discomfort, instability, and decreased mobility. You may not be able to give your dog an aspirin from the medicine cabinet, but there are plenty of pet-safe pain relievers that you can offer your dog to reduce inflammation and ease their pain.


What to look for in a pain reliever for your dog

You should always be mindful of what you feed your dog, especially when it comes to pharmaceutical-grade supplements. It’s important to purchase products from established, reputable manufacturers, and you should always check the label to see what the active ingredients are. As you’re considering your options, here are a few things to look for and a couple of things to watch out for:

  • Natural anti-inflammatories – instead of popping an aspirin, look for natural solutions with turmeric, white willow bark, MSM, pineapple bromelain, chondroitin, and glucosamine. These have natural anti-inflammatory properties to safely relieve your dog’s pain.
  • Glucosamine – this is a naturally occurring chemical compound in a dog’s body that fights inflammation and possesses anti-aging properties. As a supplement, it’s crucial in building and maintaining healthy joints.
  • MSM – in addition to fighting inflammation, this natural sulfur compound helps to relieve pain and improve joint flexibility.
  • Chondroitin – plays a big role in growing and maintaining healthy cartilage. It can naturally lubricate joints by attracting fluid to the surrounding connective tissues.
  • Turmeric – on top of being a good anti-inflammatory agent, turmeric promotes a healthy heart, brain, liver, and joints.
  • Aspirin – aspirin-based supplements will usually be the most effective pain relievers, but they can be hard on a dog’s stomach and digestive system. Use these sparingly.
  • Powdered supplements – I’m not the biggest fan of powdered supplements, as they often harden into clumps and smell terrible. It’s definitely a personal preference, but I’d personally recommend going with chewable treats and tablets instead.


Vet’s Best Aches + Pains Dog Supplements

Vet's Best pain reliever for dogs

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Vet’s Best Aches + Pains Dog Supplements offer an all-natural solution to quickly relieve sore muscles, stiff joints, and temporary discomfort. It’s an ideal choice for senior dogs as well as younger, highly active dogs. All Vet’s Best products are formulated by veterinarians with a thorough understanding of animal medicine, so you can trust that you’re using a safe, quality solution. This particular supplement is also approved by the National Animal Supplement Council (NASC).


  • Natural, aspirin-free formula with white willow bark, MSM, pineapple bromelain, and glucosamine HCL.
  • Made in the USA
  • Bottle contains 50 chewable tablets


Nutri-Vet® K-9 Aspirin

best Nutri-Vet pain reliever for dogs

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If you’re looking for a strong, aspirin-based pain reliever, I’d definitely recommend Nutri-Vet K9 Aspirin. Each chewable tablet contains 300mg of aspirin to relieve pain and inflammation, and the liver flavor makes it easy to administer to your dog by mouth. All Nutri-Vet bone and joint supplements are engineered to bolster the structural integrity of your dog’s joints and connective tissues, so you’re not just treating the pain—you’re providing the nutrients they need to heal and grow stronger.


  • Chewable tablets for medium – large dogs (50+ pounds)
  • Contains 300mg of aspirin
  • Made in the USA
  • Bottle contains 75 chewable tablets


Veterinary Naturals Extra Strength Hip & Joint Supplement

Best Veterinary Naturals pain reliever for dogs

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These Extra Strength Hip & Joint chews do a great job of easing pain and inflammation while strengthening hips and joints. They’re a good choice for dogs with joint pain, arthritis, and hip dysplasia, but they can also be used as a supplement to prevent these problems, too. Feed them to your dog at the onset of any noticeable pain, stiff joints, or reduced mobility, and you’ll be amazed at how quickly the benefits kick in.


  • Chicken and liver flavor
  • Contains glucosamine, chondroitin, MSM, organic turmeric, cold water fish oils, linoleic acid, linolenic acid, and organic turmeric for instant pain relief and increased mobility
  • Lubricates joints and strengthens cartilage to improve overall joint health and vitality
  • All-natural, 100% organic with no fillers like wheat, corn, or soy
  • Bottle contains 60 chewable tablets


ActivePet Extra Strength Joint & Hip Supplement

best ActivePet pain reliever for dogs

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Here’s another great all-natural supplement for pain relief. The ActivePet Extra Strength Joint & Hip Supplement is a beef-flavored chewable tablet that’s packed with MSM, glucosamine, and chondroitin. Like the other products that we’ve discussed, it works to naturally soothe pain and inflammation while strengthening joints to improve mobility.


  • Delicious beef flavor with an easy-to-chew, bitesize chewable tablet
  • Includes MSM, glucosamine, chondroitin, and antioxidants to relieve joint pain and inflammation
  • Lubricates and strengthens joints for increased mobility
  • Made in the USA
  • Bottle contains 120 chewable tablets


Amazing Nutritionals Turmeric Chews

best Amazing Nutritionals pain reliever for dogs

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Amazing Nutritionals Turmeric Chews are a proprietary, custom-formulated doggy treat that provides a natural pain reliever with a holistic nutritional boost for dogs of every size and age. They’re made fresh in small batches in a GMP organic-certified facility, and all of the ingredients are tested by a third-party to ensure quality, purity, and accurate dosage.

The primary ingredient is turmeric curcumin, a powerful antioxidant derived from pure turmeric root that has been proven to reduce painful joint inflammation and promote a healthy heart, liver, and joints. It packs a bacon and beef liver flavor that your dog will crave, and it’s a great treat for dogs with a sensitive stomach who can’t take pouches or pills.


  • Bacon and beef liver flavor that your dog will love
  • Pure turmeric curcumin antioxidants support a healthy heart, brain, liver, immune system, joints, and cartilage
  • Packed with vitamins, Omega 3 fatty acid, salmon fish oil, probiotics, glucosamine, chondroitin, MSM
  • Contains a natural pharmaceutical-grade anti-inflammatory formula to relieve pain from rheumatoid arthritis, hip dysplasia, and inflammation
  • No byproducts or fillers like wheat, corn, or soy
  • Hypoallergenic solution helps with skin and coat conditions such as itchy skin, hot spots, and flaking
  • Gluten-free, grain-free
  • Made in the USA
  • Bottle contains 120 chews



Each of these supplements come highly reviewed and widely recommended, so you can’t go wrong with any of them. I’d recommend getting the Nutri-Vet K9 Aspirin for emergencies (use sparingly) along with an all-natural supplement for daily use. A good all-natural solution should ease your dog’s pain while helping to strengthen their muscles, joints, and cartilage for better long-term mobility.